Cardiovascular

Performance of a machine learning algorithm to predict future blood pressure in adults on anti-hypertensive therapy in primary care

NHS
Date of Ethical Approval: August 2026
Project Identifier: SDE_LDN_PROJ_310

Project Overview

This study will validate and refine a machine-learning model using diverse NCL primary care data to predict blood pressure response to treatment, supporting personalised hypertension management and future clinical decision-support tools

Public Benefit Statement

The project is a research collaboration between QMUL clinicians, data scientists and machine learning experts, and Barnet PCRU – that allows cutting edge scientific research and knowledge exchange to take place between academic and community settings. The project is already engaging future primary users (GPs, nurses and pharmacists) who will apply project outputs to tailor BP management, and is expected to lead to high impact academic publications for the wider scientific and clinical community. The immediate objective is to validate ML BP prediction model using anonymised UK primarycare data, generating robust evidence of real-world accuracy, fairness, and generalisability. Completion of this step will de-risk the technology technically and clinically, producing a development-ready asset for next-stage funding and partnerships. The project lays the groundwork for large-scale grant applications and clinical testing in partnership with GP colleagues which, if successful, would enable commercialisation as a standalone app or integration into existing healthcare platforms. The collaboration is being highlighted in the NIHR Barts BRC renewal application to further the currently funded hypertension workstream as a partnership that will facilitate translation of research in community settings.
Current project status: Live - Contracts Signed
Is London SDE the lead SDE in this project? yes
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